Streptozotocin as a tool for induction of rat models of diabetes

Streptozotocin (STZ) is the most used diabetogenic chemical for creating rat models of type 1 and type 2 diabetes. Despite ~60 years of using STZ in animal diabetes research, some prevailing views about STZ preparation and use are not supported by evidence. Here, we provide practical guides for usin...

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Bibliographic Details
Main Authors: Asghar Ghasemi, Sajad Jeddi
Format: Article
Language:English
Published: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund 2023-02-01
Series:EXCLI Journal : Experimental and Clinical Sciences
Subjects:
Online Access:https://www.excli.de/index.php/excli/article/view/5720