Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression

Abstract Background Human immunodeficiency virus type 1 (HIV-1) Tat protein plays an essential role in HIV-1 gene transcription. Tat transactivates HIV-1 long terminal repeat (LTR)-directed gene expression through direct interactions with the transactivation-responsive region (TAR) element and other...

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Bibliographic Details
Main Authors: Meng Wang, Wei Yang, Yu Chen, Jian Wang, Juan Tan, Wentao Qiao
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Retrovirology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12977-018-0447-9