Fibroblasts From Idiopathic Pulmonary Fibrosis Induce Apoptosis and Reduce the Migration Capacity of T Lymphocytes

Fibroblasts From Idiopathic Pulmonary Fibrosis Induce Apoptosis and Reduce the Migration Capacity of T Lymphocytes

Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible lung disease of unknown etiology. Myofibroblasts are organized in peculiar subepithelial fibroblasts foci (FF), where they abnormally persist and exclude lymphocytes by unclear mechanisms. FF are the source of an excessive extrace...

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Bibliographic Details
Main Authors: Leslie Chavez-Galan, Carina Becerril, Andy Ruiz, Lucero A. Ramon-Luing, José Cisneros, Martha Montaño, Alfonso Salgado, Carlos Ramos, Ivette Buendía-Roldán, Annie Pardo, Moisés Selman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
idiopathic pulmonary fibrosis
T cells
apoptosis
migration
fibrotic focus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.820347/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.820347/full

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