Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

Guanylate-binding proteins (GBPs) belong to the dynamin family of large GTPases and represent the major IFN-γ-induced proteins. Here we systematically investigated the mechanisms regulating the subcellular localization of GBPs. Three GBPs (GBP-1, GBP-2 and GBP-5) carry a C-terminal CaaX-prenylation...

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Bibliographic Details
Main Authors: Nathalie Britzen-Laurent, Michael Bauer, Valeria Berton, Nicole Fischer, Adrian Syguda, Simone Reipschläger, Elisabeth Naschberger, Christian Herrmann, Michael Stürzl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151871/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151871/?tool=EBI

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