1IFN-α Modulates Memory Tfh Cells and Memory B Cells in Mice, Following Recombinant FMDV Adenoviral Challenge

1IFN-α Modulates Memory Tfh Cells and Memory B Cells in Mice, Following Recombinant FMDV Adenoviral Challenge

Follicular helper T (Tfh) cells regulate high-affinity antibody production. Some findings have indicated that Tfh cells could be differentiated into memory cells. Here we have investigated the effects of IFN-α, as an adjuvant, on the generation of memory Tfh cell and memory B cell responses. The dat...

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Bibliographic Details
Main Authors: Xiangguo Duan, Peng Sun, Yaru Lan, Chunxiu Shen, Xiaoyu Zhang, Shaozhang Hou, Jian Chen, Bin Ma, Yuhan Xia, Chunxia Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
IFN-α
foot-and-mouth disease recombinant adenovirus vaccine
immune memory
memory Tfh cell
memory B cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00701/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00701/full

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