Combined with UPLC-Triple-TOF/MS-based plasma lipidomics and molecular pharmacology reveals the mechanisms of schisandrin against Alzheimer’s disease

Combined with UPLC-Triple-TOF/MS-based plasma lipidomics and molecular pharmacology reveals the mechanisms of schisandrin against Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD), a type of neurodegeneration disease, is characterized by Aβ deposition and tangles of nerve fibers. Schisandrin is one of the main components of Fructus Schisandrae Chinensis. Researches showed that schisandrin can improve the cognitive impairment and me...

Full description

Bibliographic Details
Main Authors: Tian-tian Zhao, Ying Zhang, Cheng-qin Zhang, Ya-fei Chang, Mei-rong Cui, Yue Sun, Wen-qian Hao, Yu-meng Yan, Shuo Gu, Yao Xie, Bin-bin Wei
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Chinese Medicine
Subjects:
Alzheimer’s disease
Schisandrin
Lipidomics
BV2 microglia
LXR
APOE
Online Access:https://doi.org/10.1186/s13020-023-00714-y

Internet

https://doi.org/10.1186/s13020-023-00714-y

Similar Items