Development of In Vitro Dry Eye Models to Study Proliferative and Anti-Inflammatory Effects of Allogeneic Serum Eye Drops

Development of In Vitro Dry Eye Models to Study Proliferative and Anti-Inflammatory Effects of Allogeneic Serum Eye Drops

This study aimed to develop valid in vitro models for preclinical evaluation of proliferative and anti-inflammatory effects of human allogeneic serum eye drops for dry eye disease (DED) treatment. A DED wound healing model was developed by analyzing the influence of coating and serum concentrations...

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Bibliographic Details
Main Authors: Silja Voß, Till Behrmann, Stephan Reichl
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
in vitro model
dry eye
allogeneic serum
wound healing
matrix metalloprotease 9
design of experiments
Online Access:https://www.mdpi.com/1422-0067/24/2/1567

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https://www.mdpi.com/1422-0067/24/2/1567

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