Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy
Abstract Increases in α-synuclein protein expression are suspected to increase the risk of the development of Parkinson’s disease (PD). A recent study has demonstrated that β2-adrenergic receptor (β2AR) agonists decrease histone acetylation in the α-synuclein gene and suppress transcription. Coupled...
Main Authors: | Hisham Abdelmotilib, Andrew B. West |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13073-017-0483-4 |
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