SPOCK1, as a potential prognostic and therapeutic biomarker for lung adenocarcinoma, is associated with epithelial-mesenchymal transition and immune evasion

SPOCK1, as a potential prognostic and therapeutic biomarker for lung adenocarcinoma, is associated with epithelial-mesenchymal transition and immune evasion

Abstract Background The occurrence of epithelial-mesenchymal transition (EMT) and immune evasion is considered to contribute to poor prognosis in lung adenocarcinoma (LUAD). Therefore, this study aims to explore the key oncogenes that promote EMT and immune evasion and reveal the expression patterns...

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Bibliographic Details
Main Authors: Yafeng Liu, Tao Han, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Zhi Xu, Yingru Xing, Ying Bai, Dong Hu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
Lung adenocarcinoma
Epithelial-mesenchymal transition
Immune evasion
TIDE
SPOCK1
Online Access:https://doi.org/10.1186/s12967-023-04616-3

Internet

https://doi.org/10.1186/s12967-023-04616-3

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