T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells

T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells

Abstract Alveolar macrophages (AMs) are critical for defense against airborne pathogens and AM dysfunction is thought to contribute to the increased burden of pulmonary infections observed in individuals living with HIV-1 (HIV). While HIV nucleic acids have been detected in AMs early in infection, c...

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Bibliographic Details
Main Authors: Abigail E. Schiff, Alice H. Linder, Shillah N. Luhembo, Stephanie Banning, Martin J. Deymier, Thomas J. Diefenbach, Amy K. Dickey, Athe M. Tsibris, Alejandro B. Balazs, Josalyn L. Cho, Benjamin D. Medoff, Gerhard Walzl, Robert J. Wilkinson, Wendy A. Burgers, Björn Corleis, Douglas S. Kwon
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82066-x

Internet

https://doi.org/10.1038/s41598-021-82066-x

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