Toxicity study in a pig model of intraperitoneal collagenase as an “enzymatic scalpel” directed to break stroma in order to generate a new perspective for peritoneal carcinomatosis approach: an experimental research
Abstract Background This study aimed to measure the toxicity resulting from collagenase administration to the peritoneal cavity in a pig model as a preliminary step to break down the stroma surrounding tumors. Methods Eight pigs were treated with 2 different collagenase concentrations previously tes...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-02-01
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Series: | World Journal of Surgical Oncology |
Online Access: | https://doi.org/10.1186/s12957-022-02524-2 |