Potential Biomarkers of Acute Ischemic Stroke Etiology Revealed by Mass Spectrometry-Based Proteomic Characterization of Formalin-Fixed Paraffin-Embedded Blood Clots

Potential Biomarkers of Acute Ischemic Stroke Etiology Revealed by Mass Spectrometry-Based Proteomic Characterization of Formalin-Fixed Paraffin-Embedded Blood Clots

Background and AimsBesides the crucial role in the treatment of acute ischemic stroke (AIS), mechanical thrombectomy represents a unique opportunity for researchers to study the retrieved clots, with the possibility of unveiling biological patterns linked to stroke pathophysiology and etiology. We a...

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Bibliographic Details
Main Authors: Rosanna Rossi, Oana Madalina Mereuta, Mariel Barbachan e Silva, Sara Molina Gil, Andrew Douglas, Abhay Pandit, Michael Gilvarry, Ray McCarthy, Shane O'Connell, Ciara Tierney, Klearchos Psychogios, Georgios Tsivgoulis, István Szikora, Turgut Tatlisumak, Alexandros Rentzos, John Thornton, Pilib Ó Broin, Karen M. Doyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neurology
Subjects:
biomarkers stroke etiology
stroke biomarkers
mass spectrometry proteomics
FFPE proteomics
thrombus proteome
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.854846/full

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https://www.frontiersin.org/articles/10.3389/fneur.2022.854846/full

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