Characterization of apolipoprotein E7 (Glu244→Lys, Glu245→Lys), a mutant apolipoprotein E associated with hyperlipidemia and atherosclerosis

Previously, a mutant apolipoprotein (apo) E, apolipoprotein E7 (Glu244→Lys, Glu245→Lys), has been identified in association with hyperlipidemia and atherosclerosis. To investigate the effects of its structural changes on lipoprotein metabolisms and its correlation with atherosclerosis, we characteri...

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Bibliographic Details
Main Authors: Taku Yamamura, Li-Ming Dong, Akira Yamamoto
Format: Article
Language:English
Published: Elsevier 1999-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520333642