Multicomponent Lipid Nanoparticles for RNA Transfection

Multicomponent Lipid Nanoparticles for RNA Transfection

Despite the wide variety of available cationic lipid platforms for the delivery of nucleic acids into cells, the optimization of their composition has not lost its relevance. The purpose of this work was to develop multi-component cationic lipid nanoparticles (LNPs) with or without a hydrophobic cor...

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Bibliographic Details
Main Authors: Nataliya Gretskaya, Mikhail Akimov, Dmitry Andreev, Anton Zalygin, Ekaterina Belitskaya, Galina Zinchenko, Elena Fomina-Ageeva, Ilya Mikhalyov, Elena Vodovozova, Vladimir Bezuglov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
lipid nanoparticles
cationic lipids
mRNA transfection
siRNA transfection
GM3 ganglioside
Online Access:https://www.mdpi.com/1999-4923/15/4/1289

Internet

https://www.mdpi.com/1999-4923/15/4/1289

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