Being Merle: The Molecular Genetic Background of the Canine Merle Mutation

The intensity of the merle pattern is determined by the length of the poly(A) tail of a repeat element which has been inserted into the boundary of intron 10 and exon 11 of the <i>PMEL17</i> locus in reverse orientation. This poly(A) tail behaves as a microsatellite, and due to replicati...

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Bibliographic Details
Main Authors: László Varga, Xénia Lénárt, Petra Zenke, László Orbán, Péter Hudák, Nóra Ninausz, Zsófia Pelles, Antal Szőke
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/6/660