Impact of the Metal Center and Leaving Group on the Anticancer Activity of Organometallic Complexes of Pyridine-2-carbothioamide

Impact of the Metal Center and Leaving Group on the Anticancer Activity of Organometallic Complexes of Pyridine-2-carbothioamide

Ru<sup>II</sup>(cym)Cl (cym = η<sup>6</sup>-<i>p</i>-cymene) complexes of pyridinecarbothioamides have shown potential for development as orally active anticancer metallodrugs, underlined by their high selectivity towards plectin as the molecular target. In order...

Full description

Bibliographic Details
Main Authors: Jahanzaib Arshad, Kelvin K. H. Tong, Sanam Movassaghi, Tilo Söhnel, Stephen M. F. Jamieson, Muhammad Hanif, Christian G. Hartinger
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
anticancer agents
bioorganometallics
metal complexes
pyridinecarbothioamide
metallodrugs
rhodium
Online Access:https://www.mdpi.com/1420-3049/26/4/833

Internet

https://www.mdpi.com/1420-3049/26/4/833

Similar Items