Tagging active neurons by soma-targeted Cal-Light

Tagging active neurons by soma-targeted Cal-Light

Techniques for tagging active neurons with high spatiotemporal precision are limited. Here the authors report soma-targeted CalLight (ST-Cal-Light) which selectively converts somatic calcium rise triggered by action potentials into gene expression, and generate a conditional ST-Cal-Light knock-in mo...

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Bibliographic Details
Main Authors: Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Krüssel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L. Huganir, Paul F. Worley, Akira Sawa, Hyung-Bae Kwon
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35406-y

Internet

https://doi.org/10.1038/s41467-022-35406-y

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