LeishIF4E1 Deletion Affects the Promastigote Proteome, Morphology, and Infectivity

ABSTRACT Leishmania parasites cycle between sand-fly vectors and mammalian hosts, adapting to changing environmental conditions by driving a stage-specific program of gene expression, which is tightly regulated by translation processes. Leishmania encodes six eIF4E orthologs (LeishIF4Es) and five eI...

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Bibliographic Details
Main Authors: Nitin Tupperwar, Rohit Shrivastava, Michal Shapira
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00625-19