CD226 identifies functional CD8+T cells in the tumor microenvironment and predicts a better outcome for human gastric cancer

It is well-known that CD226 serves as a critical activating receptor on various immune cells, such as lymphocytes and monocytes, and it is suggested to promote anti-tumor immunity in the tumor microenvironment (TME). Herein, we showed a crucial regulatory role of CD226 in CD8+T cell-mediated anti-tu...

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Bibliographic Details
Main Authors: Hao Huang, Ziyi Huang, Junwei Ge, Jiayi Yang, Junjun Chen, Bin Xu, Shaoxian Wu, Xiao Zheng, Lujun Chen, Xueguang Zhang, Jingting Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1150803/full