Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.

Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.

Acute tubular necrosis (ATN) caused by ischemia/reperfusion (I/R) during renal transplantation delays allograft function. Identification of factors that mediate protection and/or epithelium recovery could help to improve graft outcome. We studied the expression, regulation and role of hypoxia induci...

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Bibliographic Details
Main Authors: Elisa Conde, Laura Alegre, Ignacio Blanco-Sánchez, David Sáenz-Morales, Elia Aguado-Fraile, Belén Ponte, Edurne Ramos, Ana Sáiz, Carlos Jiménez, Angel Ordoñez, Manuel López-Cabrera, Luis del Peso, Manuel O de Landázuri, Fernando Liaño, Rafael Selgas, Jose Antonio Sanchez-Tomero, María Laura García-Bermejo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3303832?pdf=render

Internet

http://europepmc.org/articles/PMC3303832?pdf=render

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