Assembly mechanism of the pleomorphic immature poxvirus scaffold

Immature poxviruses are characterized by nonicosahedral semiordered protein scaffolds critical for morphogenesis. Here, the authors use cryo-EM structures of Vaccinia virus D13 scaffold intermediates to explain their assembly mechanism.

Bibliographic Details
Main Authors: Jaekyung Hyun, Hideyuki Matsunami, Tae Gyun Kim, Matthias Wolf
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29305-5