Assembly mechanism of the pleomorphic immature poxvirus scaffold
Immature poxviruses are characterized by nonicosahedral semiordered protein scaffolds critical for morphogenesis. Here, the authors use cryo-EM structures of Vaccinia virus D13 scaffold intermediates to explain their assembly mechanism.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-29305-5 |
| _version_ | 1818774006364372992 |
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| author | Jaekyung Hyun Hideyuki Matsunami Tae Gyun Kim Matthias Wolf |
| author_facet | Jaekyung Hyun Hideyuki Matsunami Tae Gyun Kim Matthias Wolf |
| author_sort | Jaekyung Hyun |
| collection | DOAJ |
| description | Immature poxviruses are characterized by nonicosahedral semiordered protein scaffolds critical for morphogenesis. Here, the authors use cryo-EM structures of Vaccinia virus D13 scaffold intermediates to explain their assembly mechanism. |
| first_indexed | 2024-12-18T10:34:17Z |
| format | Article |
| id | doaj.art-0c380f89842c49e48f9791070560ca5a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T10:34:17Z |
| publishDate | 2022-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-0c380f89842c49e48f9791070560ca5a2022-12-21T21:10:48ZengNature PortfolioNature Communications2041-17232022-03-0113111010.1038/s41467-022-29305-5Assembly mechanism of the pleomorphic immature poxvirus scaffoldJaekyung Hyun0Hideyuki Matsunami1Tae Gyun Kim2Matthias Wolf3Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate UniversityMolecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate UniversityMolecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate UniversityMolecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate UniversityImmature poxviruses are characterized by nonicosahedral semiordered protein scaffolds critical for morphogenesis. Here, the authors use cryo-EM structures of Vaccinia virus D13 scaffold intermediates to explain their assembly mechanism.https://doi.org/10.1038/s41467-022-29305-5 |
| spellingShingle | Jaekyung Hyun Hideyuki Matsunami Tae Gyun Kim Matthias Wolf Assembly mechanism of the pleomorphic immature poxvirus scaffold Nature Communications |
| title | Assembly mechanism of the pleomorphic immature poxvirus scaffold |
| title_full | Assembly mechanism of the pleomorphic immature poxvirus scaffold |
| title_fullStr | Assembly mechanism of the pleomorphic immature poxvirus scaffold |
| title_full_unstemmed | Assembly mechanism of the pleomorphic immature poxvirus scaffold |
| title_short | Assembly mechanism of the pleomorphic immature poxvirus scaffold |
| title_sort | assembly mechanism of the pleomorphic immature poxvirus scaffold |
| url | https://doi.org/10.1038/s41467-022-29305-5 |
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