Highly Hydrophilic and Lipophilic Derivatives of Bile Salts

Highly Hydrophilic and Lipophilic Derivatives of Bile Salts

Lipophilicity of 15 derivatives of sodium cholate, defined by the octan-1-ol/water partition coefficient (<i>log P</i>), has been theoretically determined by the <i>Virtual</i> <i>log P</i> method. These derivatives bear highly hydrophobic or highly hydrophilic su...

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Bibliographic Details
Main Authors: M. Pilar Vázquez-Tato, Julio A. Seijas, Francisco Meijide, Francisco Fraga, Santiago de Frutos, Javier Miragaya, Juan Ventura Trillo, Aida Jover, Victor H. Soto, José Vázquez Tato
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
bile acids and salts
partition coefficient
isothermal titration calorimetry
hydrophilic-lipophilic balance
lipophilicity
demicellization thermodynamics
Online Access:https://www.mdpi.com/1422-0067/22/13/6684

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https://www.mdpi.com/1422-0067/22/13/6684

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