(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus

(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus

BackgroundSystemic lupus erythematosus (SLE) is a chronic autoimmune/inflammatory disease. The heterogeneity and complexity of clinical presentation has made it challenging to study or treat this syndrome. The (NZW×BXSB) F1 lupus-prone male mouse model of this disease is potentially useful to study...

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Bibliographic Details
Main Authors: Ruqayyah J. Almizraq, Kayluz Frias Boligan, Melika Loriamini, Colin McKerlie, Donald R. Branch
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
lupus erythematosus
sle
endogenous mouse model
autoimmune disease
physical and clinical characteristics
autoantibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.977698/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.977698/full

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