Nigericin is effective against multidrug resistant gram-positive bacteria, persisters, and biofilms

Nigericin is effective against multidrug resistant gram-positive bacteria, persisters, and biofilms

Multidrug-resistant (MDR) bacteria pose a significant clinical threat to human health, but the development of antibiotics cannot meet the urgent need for effective agents, especially those that can kill persisters and biofilms. Here, we reported that nigericin showed potent bactericidal activity aga...

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Bibliographic Details
Main Authors: Xiaoli Zhu, Anjin Hong, Xihuan Sun, Weijie Wang, Guanghui He, Huan Luo, Zhenhua Wu, Qingyan Xu, Zhiyu Hu, Xiaobing Wu, Donghong Huang, Li Li, Xilin Zhao, Xianming Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
multidrug-resistant bacteria
persister
biofilm
MRSA
antibiotic
mechanism of action
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1055929/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1055929/full

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