Relation between NOD2 genotype and changes in innate signaling in Crohn’s disease on mRNA and miRNA levels

Relation between NOD2 genotype and changes in innate signaling in Crohn’s disease on mRNA and miRNA levels

Crohn’s disease: Genetics impacts molecular regulation of innate immunity on miRNA, but not gene level The genetics of people with Crohn’s disease affects the molecular drivers of their dysregulated immune responses. Some individuals with Crohn’s harbor mutations in the NOD2 gene, which encodes a pa...

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Bibliographic Details
Main Authors: Yun Chen, Mohammad Salem, Mette Boyd, Jette Bornholdt, Yuan Li, Mehmet Coskun, Jakob Benedict Seidelin, Albin Sandelin, Ole Haagen Nielsen
Format: Article
Language:English
Published: Nature Portfolio 2017-02-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-016-0001-4

Internet

https://doi.org/10.1038/s41525-016-0001-4

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