Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4

Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4

TCR-like chimeric antigen receptor (CAR-T) cell therapy has emerged as a game-changing strategy in cancer immunotherapy, offering a broad spectrum of potential antigen targets, particularly in solid tumors containing intracellular antigens. In this study, we investigated the cytotoxicity and functio...

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Bibliographic Details
Main Authors: Alaa Alsalloum, Julia Shevchenko, Marina Fisher, Julia Philippova, Roman Perik-Zavodskii, Olga Perik-Zavodskaia, Saleh Alrhmoun, Julia Lopatnikova, Kurilin Vasily, Marina Volynets, Evgenii Zavjalov, Olga Solovjeva, Yasushi Akahori, Hiroshi Shiku, Alexander Silkov, Sergey Sennikov
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
TCR-like CAR-T cells
MAGE-A4
GITR
cytotoxicity
Nanostring
Online Access:https://www.mdpi.com/1422-0067/24/20/15134

Internet

https://www.mdpi.com/1422-0067/24/20/15134

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