Lipid raft localization of TLR2 and its co-receptors is independent of membrane lipid composition

Background Toll like receptors (TLRs) are an important and evolutionary conserved class of pattern recognition receptors associated with innate immunity. The recognition of Gram-positive cell wall constituents strongly depends on TLR2. In order to be functional, TLR2 predominantly forms a heterodime...

Full description

Bibliographic Details
Main Authors: Christine Hellwing, Axel Schoeniger, Claudia Roessler, Anja Leimert, Julia Schumann
Format: Article
Language:English
Published: PeerJ Inc. 2018-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/4212.pdf