Effect of Mycobacterium leprae on neurotrophins expression in human Schwann cells and mouse sciatic nerves

BACKGROUND Although Mycobacterium leprae (ML) is well characterised as the causative agent of leprosy, the pathophysiological mechanisms underlying peripheral nerve damage still need further understanding. In vitro and in vivo studies have yielded insights into molecular mechanisms of ML interactio...

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Bibliographic Details
Main Authors: Maria Renata Sales Nogueira, Nádia Ghinelli Amôr, Letícia Baccaro Michellin, Milton Cury Filho, Patrícia Sammarco Rosa, Ana Carla Pereira Latini, Luciana Silva Rodrigues, Robertha Mariana Rodrigues Lemes, Flavio Alves Lara, Maria Cristina Vidal Pessolani
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2020-07-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/pdf/mioc/v115/1678-8060-mioc-115-e200075.pdf