Inhibition of epidermal growth factor receptor suppresses parathyroid hormone‐related protein expression in tumours and ameliorates cancer‐associated cachexia

Inhibition of epidermal growth factor receptor suppresses parathyroid hormone‐related protein expression in tumours and ameliorates cancer‐associated cachexia

Abstract Background Lung cancer is the primary cause of cancer deaths worldwide. Activation of epidermal growth factor receptor (EGFR) leads to lung cancer progression and poor prognosis while involuntary weight loss remains a major problem. Tumour‐derived parathyroid hormone‐related protein (PTHrP)...

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Bibliographic Details
Main Authors: Bahar Zehra Camurdanoglu Weber, Samet Agca, Aylin Domaniku, Sevval Nur Bilgic, Dilsad H. Arabaci, Serkan Kir
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Epidermal growth factor receptor (EGFR)
EGFR inhibitors
Parathyroid hormone‐related protein (PTHrP)
Lung cancer
Cancer‐associated cachexia
Online Access:https://doi.org/10.1002/jcsm.12985

Internet

https://doi.org/10.1002/jcsm.12985

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