Targeting Heat-Shock Protein 90 in Cancer: An Update on Combination Therapy

Targeting Heat-Shock Protein 90 in Cancer: An Update on Combination Therapy

Heat-shock protein 90 (HSP90) is an important molecule chaperone associated with tumorigenesis and malignancy. HSP90 is involved in the folding and maturation of a wide range of oncogenic clients, including diverse kinases, transcription factors and oncogenic fusion proteins. Therefore, it could be...

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Bibliographic Details
Main Authors: Xiude Ren, Tao Li, Wei Zhang, Xuejun Yang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
heat-shock protein 90 inhibitors
molecular chaperones
HSP90
cancer therapy
combinational therapy
Online Access:https://www.mdpi.com/2073-4409/11/16/2556

Internet

https://www.mdpi.com/2073-4409/11/16/2556

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