Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks: a randomized controlled trial.

BACKGROUND: At present, there is insufficient evidence to guide appropriate management of women with preterm prelabor rupture of membranes (PPROM) near term. METHODS AND FINDINGS: We conducted an open-label randomized controlled trial in 60 hospitals in The Netherlands, which included non-laboring w...

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Main Authors: David P van der Ham, Sylvia M C Vijgen, Jan G Nijhuis, Johannes J van Beek, Brent C Opmeer, Antonius L M Mulder, Rob Moonen, Mariët Groenewout, Mariëlle G van Pampus, Gerald D Mantel, Kitty W M Bloemenkamp, Wim J van Wijngaarden, Marko Sikkema, Monique C Haak, Paula J M Pernet, Martina Porath, Jan F M Molkenboer, Simone Kuppens, Anneke Kwee, Michael E Kars, Mallory Woiski, Martin J N Weinans, Hajo I J Wildschut, Bettina M C Akerboom, Ben W J Mol, Christine Willekes, PPROMEXIL trial group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC3335867?pdf=render