Zidebactam restores sulbactam susceptibility against carbapenem-resistant Acinetobacter baumannii isolates

Zidebactam restores sulbactam susceptibility against carbapenem-resistant Acinetobacter baumannii isolates

Carbapenems are commonly used to treat infections caused by multidrug-resistant (MDR) bacteria. Unfortunately, carbapenem resistance is increasingly reported in many gram-negative bacteria, especially Acinetobacter baumannii. Diazabicyclooctane (DBO) β-lactamase inhibitors, such as avibactam (AVI),...

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Bibliographic Details
Main Authors: Jose Cedano, Michelle Baez, Fernando Pasteran, Sabrina Daiana Montaña, Grace Ra, Venjaminne Fua, Alejandra Corso, Marcelo E. Tolmasky, Robert A. Bonomo, María Soledad Ramírez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Acinetobacter
carbapenem-resistance
zidebactam
sulbactam
DBOs
synergy
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.918868/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.918868/full

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