Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.

Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.

It has been suggested that receptor-ligand complexes segregate or co-localise within immune synapses according to their size, and this is important for receptor signaling. Here, we set out to test the importance of receptor-ligand complex dimensions for immune surveillance of target cells by human N...

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Bibliographic Details
Main Authors: Karsten Köhler, Shiqiu Xiong, Joanna Brzostek, Maryam Mehrabi, Philipp Eissmann, Alice Harrison, Shaun-Paul Cordoba, Stephane Oddos, Vladimir Miloserdov, Keith Gould, Nigel J Burroughs, Philip Anton van der Merwe, Daniel M Davis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3001952?pdf=render

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http://europepmc.org/articles/PMC3001952?pdf=render

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