Protective potential of piroxicam on human peripheral blood mononuclear cells against the suppressive capacity of glioblastoma cell lines

Abstract Dexamethasone, a common medication used in the treatment regimen of glioblastoma, has broad inhibitory effects on the immune responses. Here, in an in vitro study, we examined the effects of piroxicam, a potent substitute for dexamethasone, on peripheral blood mononuclear cells (PBMCs) co-c...

Full description

Bibliographic Details
Main Authors: Jahangir Abdesheikhi, Farnaz Sedghy, Alireza Farsinejad, Merat Mahmoudi, Mahdi ranjkesh, Meysam Ahmadi-Zeidabadi
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24392-2