Evaluation of the Safety and Effectiveness of Topical Intrapleural Application of Tranexamic Acid in Thoracic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Objectives Bleeding remains a common complication post-thoracic surgery. Although intravenous tranexamic acid (TXA) has been shown to decrease blood loss, its use has been associated with adverse effects. Accordingly, topical TXA has been proposed as an alternative to reduce bleeding with fewer syst...

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Bibliographic Details
Main Authors: Amer Alzahrani MD RRT, Hadeel Alkofide Ph.D., Hala Joharji PharmD, Ghazwa B. Korayem PharmD, Sarah Aljohani PharmD, Hanan Alshareef PharmD, Mashael AlFaifi PharmD, Hassan Alalawi MBBS, Khalid Al Sulaiman BCCCP, BCNSP, MBA, FCCM
Format: Article
Language:English
Published: SAGE Publishing 2023-12-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296231218215