Ack1: activation and regulation by allostery.

The non-receptor tyrosine kinase Ack1 belongs to a unique multi-domain protein kinase family, Ack. Ack is the only family of SH3 domain containing kinases to have an SH3 domain following the kinase domain; others have their SH3 domains preceding the kinase domain. Previous reports have suggested tha...

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Bibliographic Details
Main Authors: Ketan S Gajiwala, Karen Maegley, RoseAnn Ferre, You-Ai He, Xiu Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544672?pdf=render