Predicting circRNA-drug sensitivity associations via graph attention auto-encoder

Predicting circRNA-drug sensitivity associations via graph attention auto-encoder

Abstract Background Circular RNAs (circRNAs) play essential roles in cancer development and therapy resistance. Many studies have shown that circRNA is closely related to human health. The expression of circRNAs also affects the sensitivity of cells to drugs, thereby significantly affecting the effi...

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Bibliographic Details
Main Authors: Lei Deng, Zixuan Liu, Yurong Qian, Jingpu Zhang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Bioinformatics
Subjects:
circRNA-drug associations
Graph attention auto-encoder
Neural network
Similarity network
Online Access:https://doi.org/10.1186/s12859-022-04694-y

Internet

https://doi.org/10.1186/s12859-022-04694-y

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