Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria

ABSTRACT Mycolic acids are the signature lipid of mycobacteria and constitute an important physical component of the cell wall, a target of mycobacterium-specific antibiotics and a mediator of Mycobacterium tuberculosis pathogenesis. Mycolic acids are synthesized in the cytoplasm and are thought to...

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Bibliographic Details
Main Authors: Allison Fay, Nadine Czudnochowski, Jeremy M. Rock, Jeffrey R. Johnson, Nevan J. Krogan, Oren Rosenberg, Michael S. Glickman
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00850-19