Role of Bruton’s Tyrosine Kinase in Stage III Colorectal Cancer

Role of Bruton’s Tyrosine Kinase in Stage III Colorectal Cancer

Background: Bruton’s tyrosine kinase (BTK) is involved in the immune response and its deficiency impairs B cell maturation. We evaluated the expression of a novel BTK isoform, p65BTK, in colorectal cancer (CRC), to identify its impact on survival. Materials and Methods: This retrospective study eval...

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Bibliographic Details
Main Authors: Debora Basile, Lorenzo Gerratana, Angela Buonadonna, Silvio Ken Garattini, Tiziana Perin, Emanuela Grassilli, Gianmaria Miolo, Maria Grazia Cerrito, Claudio Belluco, Giulio Bertola, Antonino De Paoli, Renato Cannizzaro, Marialuisa Lavitrano, Fabio Puglisi, Vincenzo Canzonieri
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
colon cancer
Bruton’s tyrosine kinase
BTK
Online Access:https://www.mdpi.com/2072-6694/11/6/880

Internet

https://www.mdpi.com/2072-6694/11/6/880

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