Human macrophage-engineered vesicles for utilization in ovarian cancer treatment

BackgroundOvarian cancer is a deadly female malignancy with a high rate of recurrent and chemotherapy-resistant disease. Tumor-associated macrophages (TAMs) are a significant component of the tumor microenvironment and include high levels of M2-protumor macrophages that promote chemoresistance and m...

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Bibliographic Details
Main Authors: David Schweer, Namrata Anand, Abigail Anderson, J. Robert McCorkle, Khaga Neupane, Alexandra N. Nail, Brock Harvey, Kristen S. Hill, Frederick Ueland, Christopher Richards, Jill Kolesar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1042730/full