Study on the mechanisms of action of berberine combined with fluconazole against fluconazole-resistant strains of Talaromyces marneffei

Study on the mechanisms of action of berberine combined with fluconazole against fluconazole-resistant strains of Talaromyces marneffei

Talaromyces (Penicillium) marneffei (T. marneffei) is a thermally dimorphic fungus that can cause opportunistic systemic mycoses. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant T. marneffei (B4) in vitro...

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Bibliographic Details
Main Authors: Pan Kai-su, Luo Hong, Zheng Dong-yan, Zheng Yan-qing, Alex Andrianopoulos, Jean-Paul Latgé, Cao Cun-wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
Talaromyces marneffei
berberine
fluconazole
fluconazole-resistant
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1033211/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1033211/full

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