Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6

Abstract Cyclooxygenase-2 catalyses the biosynthesis of prostaglandins from arachidonic acid but also the biosynthesis of prostaglandin glycerol esters (PG-Gs) from 2-arachidonoylglycerol. Previous studies identified PG-Gs as signalling molecules involved in inflammation. Thus, the glyceryl ester of...

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Bibliographic Details
Main Authors: Antje Brüser, Anne Zimmermann, Brenda C. Crews, Gregory Sliwoski, Jens Meiler, Gabriele M. König, Evi Kostenis, Vera Lede, Lawrence J. Marnett, Torsten Schöneberg
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02414-8

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https://doi.org/10.1038/s41598-017-02414-8

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