An efficient and scalable data analysis solution for automated electrophysiology platforms

An efficient and scalable data analysis solution for automated electrophysiology platforms

Ion channels are drug targets for neurologic, cardiac, and immunologic diseases. Many disease-associated mutations and drugs modulate voltage-gated ion channel activation and inactivation, suggesting that characterizing state-dependent effects of test compounds at an early stage of drug development...

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Bibliographic Details
Main Authors: Tianbo Li, Martin Ginkel, Ada X. Yee, Leigh Foster, Jun Chen, Stephan Heyse, Stephan Steigele
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:SLAS Discovery
Subjects:
Automated patch clamp
Electrophysiology
High-throughput screening
Data analysis
Ion channel
Online Access:http://www.sciencedirect.com/science/article/pii/S2472555221000162

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http://www.sciencedirect.com/science/article/pii/S2472555221000162

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