Clinical and molecular characteristics of sickle cell anemia in the northeast of Brazil

Clinical and molecular characteristics of sickle cell anemia in the northeast of Brazil

Beta S-globin gene (βS-globin) haplotypes, markers for severe sickle cell anemia (SCA), and the alpha-thalassemia 2 gene 3.7 kb deletion (-α2(3.7 kb) thal) along with demographic and clinical data were investigated in SCA outpatients (n = 125, 63 female and 62 male) in the Brazilia...

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Bibliographic Details
Main Authors: Elisângela Vitória Adorno, Ângela Zanette, Isa Lyra, Magda Oliveira Seixas, Mitermayer Galvão Reis, Marilda Souza Gonçalves
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2008-01-01
Series:Genetics and Molecular Biology
Subjects:
alpha-thalassemia 2 gene 3.7 kb deletion (-α23.7 kb thal)
βS-globin gene haplotypes
Fetal hemoglobin
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400003

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400003

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