MicroRNA-target binding structures mimic microRNA duplex structures in humans.

Traditionally, researchers match a microRNA guide strand to mRNA sequences using sequence comparisons to predict its potential target genes. However, many of the predictions can be false positives due to limitations in sequence comparison alone. In this work, we consider the association of two relat...

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Bibliographic Details
Main Authors: Xi Chen, Lu Shen, Hui-Hsien Chou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923817?pdf=render