Expression of key cytokines in dog macrophages infected by Leishmania tarentolae opening new avenues for the protection against Leishmania infantum

Abstract The detection of Leishmania tarentolae in sympatric areas where Leishmania infantum is endemic raised questions regarding the protective effect exerted in dogs by L. tarentolae when in coinfection. This study aimed monitoring the in vitro gene expression of pro- (IFN- γ; TNF-α; IL-12) and a...

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Main Authors: Viviane Noll Louzada-Flores, Maria Stefania Latrofa, Jairo Alfonso Mendoza-Roldan, Maria Stella Lucente, Sara Epis, Ilaria Varotto-Boccazzi, Claudio Bandi, Domenico Otranto
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-78451-x