Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells
The transcriptional programs of nuclei in the muscle syncytium were assumed to be homogenous except at the neuromuscular and myotendinous junctions. Here, using single-nucleus transcriptomics, the authors reveal a previously unrecognized diversity and dynamics of myonuclear transcriptional programs.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20064-9 |