Increased maternal non-oxidative energy metabolism mediates association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and offspring autism spectrum disorder symptoms in early life: A birth cohort study

Increased maternal non-oxidative energy metabolism mediates association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and offspring autism spectrum disorder symptoms in early life: A birth cohort study

Prenatal phthalate exposure has previously been linked to the development of autism spectrum disorder (ASD). However, the underlying biological mechanisms remain unclear. We investigated whether maternal and child central carbon metabolism is involved as part of the Barwon Infant Study (BIS), a popu...

Full description

Bibliographic Details
Main Authors: Sarah Thomson, Katherine Drummond, Martin O'Hely, Christos Symeonides, Chitra Chandran, Toby Mansell, Richard Saffery, Peter Sly, Jochen Mueller, Peter Vuillermin, Anne-Louise Ponsonby
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Environment International
Subjects:
Endocrine disrupting chemicals
Metabolomics
Pyruvate metabolism
Warburg Effect
Autism spectrum disorder
Neurodevelopment
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412022006055

Internet

http://www.sciencedirect.com/science/article/pii/S0160412022006055

Similar Items