Dapagliflozin Does Not Protect against Adriamycin-Induced Kidney Injury in Mice

Dapagliflozin Does Not Protect against Adriamycin-Induced Kidney Injury in Mice

Introduction: Sodium-glucose cotransporter 2 (SGLT2) inhibitors target SGLT2 in renal proximal tubules and promote glycosuria in type 2 diabetes mellitus in humans and animal models, resulting in reduced blood glucose levels. Although clinical trials have shown that SGLT2 inhibitors attenuate the pr...

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Bibliographic Details
Main Authors: Jin Joo Cha, Hye-jin Park, Ji Ae Yoo, Jungyeon Ghee, Dae Ryong Cha, Young Sun Kang
Format: Article
Language:English
Published: Karger Publishers 2024-01-01
Series:Kidney & Blood Pressure Research
Subjects:
dapagliflozin
adriamycin
nephropathy
acute kidney injury
sglt2 inhibitor
Online Access:https://beta.karger.com/Article/FullText/536088

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